Carregant...
Evaluating the Effects of Hinge Flexibility on the Solution Structure of Antibodies at Concentrated Conditions
Employing two different coarse-grained models, we evaluated the effect of intramolecular domain-domain distances and hinge flexibility on the general solution structure of antibodies (mAbs), within the context of protein-protein steric repulsion. These models explicitly account for the hinge region,...
Guardat en:
| Publicat a: | J Pharm Sci |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7288351/ https://ncbi.nlm.nih.gov/pubmed/30593783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2018.12.013 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|