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Flexible antibodies with nonprotein hinges
There is a significant need for antibodies that can bind targets with greater affinity. Here we describe a novel strategy employing chemical semisynthesis to produce symmetroadhesins: antibody-like molecules having nonprotein hinge regions that are more flexible and extendible and are capable of two...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Japan Academy
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3309923/ https://ncbi.nlm.nih.gov/pubmed/22075761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2183/pjab.87.603 |
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