Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging

Monocarboxylate transporters 1-4 (MCT1-4) are involved in several metabolism-related diseases, especially cancer, providing the chance to be considered as relevant targets for diagnosis and therapy. [(18)F]FACH was recently developed and showed very promising preclinical results as a potential posit...

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Publicado no:Molecules
Main Authors: Sadeghzadeh, Masoud, Wenzel, Barbara, Gündel, Daniel, Deuther-Conrad, Winnie, Toussaint, Magali, Moldovan, Rareş-Petru, Fischer, Steffen, Ludwig, Friedrich-Alexander, Teodoro, Rodrigo, Jonnalagadda, Shirisha, Jonnalagadda, Sravan K., Schüürmann, Gerrit, Mereddy, Venkatram R., Drewes, Lester R., Brust, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7288138/
https://ncbi.nlm.nih.gov/pubmed/32423056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102309
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