Hypoxia-Activated Prodrug Derivatives of Carbonic Anhydrase Inhibitors in Benzenesulfonamide Series: Synthesis and Biological Evaluation

Hypoxia, a common feature of solid tumours’ microenvironment, is associated with an aggressive phenotype and is known to cause resistance to anticancer chemo- and radiotherapies. Tumour-associated carbonic anhydrases isoform IX (hCA IX), which is upregulated under hypoxia in many malignancies partic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Anduran, Emilie, Aspatwar, Ashok, Parvathaneni, Nanda-Kumar, Suylen, Dennis, Bua, Silvia, Nocentini, Alessio, Parkkila, Seppo, Supuran, Claudiu T., Dubois, Ludwig, Lambin, Philippe, Winum, Jean-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7287649/
https://ncbi.nlm.nih.gov/pubmed/32443462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules25102347
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados