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Afterdepolarizations and abnormal calcium handling in atrial myocytes with modulated SERCA uptake: a sensitivity analysis of calcium handling channels
Delayed afterdepolarizations (DADs) and spontaneous depolarizations (SDs) are typically triggered by spontaneous diastolic Ca(2+) release from the sarcoplasmic reticulum (SR) which is caused by an elevated SR Ca(2+)-ATPase (SERCA) uptake and dysfunctional ryanodine receptors. However, recent studies...
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| Publicado no: | Philos Trans A Math Phys Eng Sci |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society Publishing
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7287332/ https://ncbi.nlm.nih.gov/pubmed/32448059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsta.2019.0557 |
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