טוען...
PITX2 upregulation increases the risk of chronic atrial fibrillation in a dose-dependent manner by modulating I(Ks) and I(CaL)—insights from human atrial modelling
BACKGROUND: Functional analysis has shown that the paired-like homeodomain transcription factor 2 (PITX2) overexpression associated with atrial fibrillation (AF) leads to the slow delayed rectifier K(+) current (I(Ks)) increase and the L-type Ca(2+) current (I(CaL)) reduction observed in isolated ri...
שמור ב:
| הוצא לאור ב: | Ann Transl Med |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
AME Publishing Company
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7154416/ https://ncbi.nlm.nih.gov/pubmed/32309338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2020.01.90 |
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