Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues

An increase in the burden of senescent cells in tissues with age contributes to driving aging and the onset of age-related diseases. Genetic and pharmacologic elimination of senescent cells extends both health span and life span in mouse models. Heterochronic parabiosis in mice has been used to iden...

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Detaylı Bibliyografya
Yayımlandı:GeroScience
Asıl Yazarlar: Yousefzadeh, Matthew J., Wilkinson, John E., Hughes, Brian, Gadela, Namrata, Ladiges, Warren C., Vo, Nam, Niedernhofer, Laura J., Huffman, Derek M., Robbins, Paul D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer International Publishing 2020
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286998/
https://ncbi.nlm.nih.gov/pubmed/32285290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00185-1
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