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Heterochronic parabiosis regulates the extent of cellular senescence in multiple tissues

An increase in the burden of senescent cells in tissues with age contributes to driving aging and the onset of age-related diseases. Genetic and pharmacologic elimination of senescent cells extends both health span and life span in mouse models. Heterochronic parabiosis in mice has been used to iden...

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Publicado en:GeroScience
Main Authors: Yousefzadeh, Matthew J., Wilkinson, John E., Hughes, Brian, Gadela, Namrata, Ladiges, Warren C., Vo, Nam, Niedernhofer, Laura J., Huffman, Derek M., Robbins, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado: Springer International Publishing 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286998/
https://ncbi.nlm.nih.gov/pubmed/32285290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-020-00185-1
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