Thyroid deficiency before birth alters the adipose transcriptome to promote overgrowth of white adipose tissue and impair thermogenic capacity

BACKGROUND: Development of adipose tissue before birth is essential for energy storage and thermoregulation in the neonate and for cardiometabolic health in later life. Thyroid hormones are important regulators of growth and maturation in fetal tissues. Offspring hypothyroid in utero are poorly adap...

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Detalhes bibliográficos
Publicado no:Thyroid
Main Authors: Harris, Shelley E, De Blasio, Miles J, Zhao, Xiaohui, Ma, Marcella, Davies, Katie, Wooding, FB Peter, Hamilton, Russell S, Blache, Dominique, Meredith, David, Murray, Andrew J, Fowden, Abigail L, Forhead, Alison J
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286741/
https://ncbi.nlm.nih.gov/pubmed/32070265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2019.0749
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