Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells

Alternative lengthening of telomeres (ALT) in human cells is a conserved process that is often activated in telomerase-deficient human cancers. This process exploits components of the recombination machinery to extend telomere ends, thus allowing for increased proliferative potential. Human MUS81 (M...

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Publicado en:PLoS Genet
Autores principales: Schwartz, Erin K., Hung, Shih-Hsun, Meyer, Damon, Piazza, Aurèle, Yan, Kevin, Fu, Becky Xu Hua, Heyer, Wolf-Dietrich
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7286520/
https://ncbi.nlm.nih.gov/pubmed/32469862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008816
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