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Format and geometries matter: Structure-based design defines the functionality of bispecific antibodies
Multispecific antibodies can be generated in different formats. More than two decades of R&D in the field of bispecific antibody engineering revealed that the design and choice of format can have a profound impact on the antibody functionality. This holds in particular true for entities that eli...
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| Publicado en: | Comput Struct Biotechnol J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7283971/ https://ncbi.nlm.nih.gov/pubmed/32542108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.05.006 |
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