A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study

BACKGROUND: A Pediatric Brain Tumor Consortium (PBTC) phase I/II trial of veliparib and radiation followed by veliparib and temozolomide (TMZ) was conducted in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG). The objectives were to: (i) estimate the recommended phase II dose (R...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Baxter, Patricia A, Su, Jack M, Onar-Thomas, Arzu, Billups, Catherine A, Li, Xiao-Nan, Poussaint, Tina Young, Smith, Edward R, Thompson, Patrick, Adesina, Adekunle, Ansell, Pete, Giranda, Vincent, Paulino, Arnold, Kilburn, Lindsey, Quaddoumi, Ibrahim, Broniscer, Alberto, Blaney, Susan M, Dunkel, Ira J, Fouladi, Maryam
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Pediatric Neuro-Oncology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7283021/
https://ncbi.nlm.nih.gov/pubmed/32009149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa016
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