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Modulation of dopamine D(1) receptors via histamine H(3) receptors is a novel therapeutic target for Huntington's disease
Early Huntington’s disease (HD) include over-activation of dopamine D(1) receptors (D(1)R), producing an imbalance in dopaminergic neurotransmission and cell death. To reduce D(1)R over-activation, we present a strategy based on targeting complexes of D(1)R and histamine H(3) receptors (H(3)R). Usin...
שמור ב:
| הוצא לאור ב: | eLife |
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| Main Authors: | , , , , , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
eLife Sciences Publications, Ltd
2020
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7282811/ https://ncbi.nlm.nih.gov/pubmed/32513388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51093 |
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