A Significant Role of the Truncated Ghrelin Receptor GHS-R1b in Ghrelin-induced Signaling in Neurons

The truncated non-signaling ghrelin receptor growth hormone secretagogue R1b (GHS-R1b) has been suggested to simply exert a dominant negative role in the trafficking and signaling of the full and functional ghrelin receptor GHS-R1a. Here we reveal a more complex modulatory role of GHS-R1b. Different...

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Vydáno v:J Biol Chem
Hlavní autoři: Navarro, Gemma, Aguinaga, David, Angelats, Edgar, Medrano, Mireia, Moreno, Estefanía, Mallol, Josefa, Cortés, Antonio, Canela, Enric I., Casadó, Vicent, McCormick, Peter J., Lluís, Carme, Ferré, Sergi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Neurobiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933222/
https://ncbi.nlm.nih.gov/pubmed/27129257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715144
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