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ULK1-ATG13 and their mitotic phospho-regulation by CDK1 connect autophagy to cell cycle

Unc-51-like autophagy activating kinase 1 (ULK1)–autophagy-related 13 (ATG13) is the most upstream autophagy initiation complex that is phosphorylated by mammalian target-of-rapamycin complex 1 (mTORC1) and AMP-activated protein kinase (AMPK) to induce autophagy in asynchronous conditions. However,...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Principais autores: Li, Zhiyuan, Tian, Xiaofei, Ji, Xinmiao, Wang, Junjun, Chen, Hanxiao, Wang, Dongmei, Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7282624/
https://ncbi.nlm.nih.gov/pubmed/32516310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000288
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