Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Cho, Sung Kweon, Kim, Beomsu, Myung, Woojae, Chang, Yoosoo, Ryu, Seungho, Kim, Han-Na, Kim, Hyung-Lae, Kuo, Po-Hsiu, Winkler, Cheryl A., Won, Hong-Hee
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280503/
https://ncbi.nlm.nih.gov/pubmed/32514006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66064-z
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