Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...

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Pubblicato in:Sci Rep
Autori principali: Cho, Sung Kweon, Kim, Beomsu, Myung, Woojae, Chang, Yoosoo, Ryu, Seungho, Kim, Han-Na, Kim, Hyung-Lae, Kuo, Po-Hsiu, Winkler, Cheryl A., Won, Hong-Hee
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280503/
https://ncbi.nlm.nih.gov/pubmed/32514006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66064-z
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