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Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Cho, Sung Kweon, Kim, Beomsu, Myung, Woojae, Chang, Yoosoo, Ryu, Seungho, Kim, Han-Na, Kim, Hyung-Lae, Kuo, Po-Hsiu, Winkler, Cheryl A., Won, Hong-Hee
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280503/
https://ncbi.nlm.nih.gov/pubmed/32514006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66064-z
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