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Polygenic analysis of the effect of common and low-frequency genetic variants on serum uric acid levels in Korean individuals

Increased serum uric acid (SUA) levels cause gout and are associated with multiple diseases, including chronic kidney disease. Previous genome-wide association studies (GWAS) have identified more than 180 loci that contribute to SUA levels. Here, we investigated genetic determinants of SUA level in...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cho, Sung Kweon, Kim, Beomsu, Myung, Woojae, Chang, Yoosoo, Ryu, Seungho, Kim, Han-Na, Kim, Hyung-Lae, Kuo, Po-Hsiu, Winkler, Cheryl A., Won, Hong-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280503/
https://ncbi.nlm.nih.gov/pubmed/32514006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-66064-z
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