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Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy

The integrated stress response is characterized by the phosphorylation of eukaryotic initiation factor-2α (eIF2α) on serine 51 by one out of four specific kinases (EIF2AK1 to 4). Here we provide three series of evidence suggesting that macroautophagy (to which we refer to as autophagy) induced by a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Humeau, Juliette, Leduc, Marion, Cerrato, Giulia, Loos, Friedemann, Kepp, Oliver, Kroemer, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280501/
https://ncbi.nlm.nih.gov/pubmed/32513922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2642-6
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