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Phosphorylation of eukaryotic initiation factor-2α (eIF2α) in autophagy

The integrated stress response is characterized by the phosphorylation of eukaryotic initiation factor-2α (eIF2α) on serine 51 by one out of four specific kinases (EIF2AK1 to 4). Here we provide three series of evidence suggesting that macroautophagy (to which we refer to as autophagy) induced by a...

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Detalles Bibliográficos
Publicado en:Cell Death Dis
Main Authors: Humeau, Juliette, Leduc, Marion, Cerrato, Giulia, Loos, Friedemann, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280501/
https://ncbi.nlm.nih.gov/pubmed/32513922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2642-6
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