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eIF2α phosphorylation: A hallmark of immunogenic cell death

Immunogenic cell death (ICD) induced by anticancer chemotherapeutics is usually preceded by premortem stress affecting the endoplasmic reticulum (ER). This ER stress does not reflect a canonical unfolded protein response (UPR) but rather manifests solely at the level of the phosphorylation of eIF2α....

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Bezu, Lucillia, Sauvat, Allan, Humeau, Juliette, Leduc, Marion, Kepp, Oliver, Kroemer, Guido
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980344/
https://ncbi.nlm.nih.gov/pubmed/29872560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1431089
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