Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production

Obesity is growing rapidly worldwide due to consumption of westernized diet and lack of exercise. Obesity is one of the major risk factors of hypertension. The novel histone deacetylase (HDAC) inhibitor CG200745 was originally developed to treat various cancers. Previous studies showed that CG200745...

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Bibliografiske detaljer
Udgivet i:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Yoon, Ga-Eun, Jung, Jin Ki, Lee, Yun-Han, Jang, Byeong-Churl, In Kim, Jee
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280340/
https://ncbi.nlm.nih.gov/pubmed/31655853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-019-01749-5
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