Histone deacetylase inhibitor CG200745 ameliorates high-fat diet-induced hypertension via inhibition of angiotensin II production

Obesity is growing rapidly worldwide due to consumption of westernized diet and lack of exercise. Obesity is one of the major risk factors of hypertension. The novel histone deacetylase (HDAC) inhibitor CG200745 was originally developed to treat various cancers. Previous studies showed that CG200745...

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Bibliographic Details
Published in:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Yoon, Ga-Eun, Jung, Jin Ki, Lee, Yun-Han, Jang, Byeong-Churl, In Kim, Jee
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7280340/
https://ncbi.nlm.nih.gov/pubmed/31655853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-019-01749-5
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