Targeted Amino Acid Substitution Overcomes Scale-Up Challenges with the Human C5a-Derived Decapeptide Immunostimulant EP67

EP67 is a second-generation, human C5a-derived decapeptide agonist of C5a Receptor 1 (C5aR1/CD88) that selectively activates mononuclear phagocytes over neutrophils to potentiate protective innate and adaptive immune responses while potentially minimizing neutrophil-mediated toxicity. Pro(7) and N-m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Infect Dis
Main Authors: Alshammari, Abdulraman M., Smith, D. David, Parriott, Jake, Stewart, Jason P., Curran, Stephen M., McCulloh, Russell J., Barry, Peter A., Iyer, Smita S., Palermo, Nicholas, Phillips, Joy A., Dong, Yuxiang, Ronning, Donald R., Vennerstrom, Jonathan L., Sanderson, Sam D., Vetro, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279522/
https://ncbi.nlm.nih.gov/pubmed/32233506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsinfecdis.0c00005
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados