Enhanced Clearance of Neurotoxic Misfolded Proteins by the Natural Compound Berberine and Its Derivatives

Background: Accumulation of misfolded proteins is a common hallmark of several neurodegenerative disorders (NDs) which results from a failure or an impairment of the protein quality control (PQC) system. The PQC system is composed by chaperones and the degradative systems (proteasome and autophagy)....

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Pubblicato in:Int J Mol Sci
Autori principali: Rusmini, Paola, Cristofani, Riccardo, Tedesco, Barbara, Ferrari, Veronica, Messi, Elio, Piccolella, Margherita, Casarotto, Elena, Chierichetti, Marta, Cicardi, Maria Elena, Galbiati, Mariarita, Geroni, Cristina, Lombardi, Paolo, Crippa, Valeria, Poletti, Angelo
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7279252/
https://ncbi.nlm.nih.gov/pubmed/32414108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21103443
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