Dual SMO/BRAF Inhibition by Flavonolignans from Silybum marianum †

Silymarin is the standardized extract from the fruits of Silybum marianum (L.) Gaertn., a well-known hepatoprotectant and antioxidant. Recently, bioactive compounds of silymarin, i.e., silybins and their 2,3-dehydro derivatives, have been shown to exert anticancer activities, yet with unclear mechan...

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Publicat a:Antioxidants (Basel)
Autors principals: Diukendjieva, Antonia, Zaharieva, Maya M., Mori, Mattia, Alov, Petko, Tsakovska, Ivanka, Pencheva, Tania, Najdenski, Hristo, Křen, Vladimír, Felici, Chiara, Bufalieri, Francesca, Di Marcotullio, Lucia, Botta, Bruno, Botta, Maurizio, Pajeva, Ilza
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278695/
https://ncbi.nlm.nih.gov/pubmed/32380762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox9050384
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