Modes-of-Action Related to Repeated Dose Toxicity: Tissue-Specific Biological Roles of PPARγ Ligand-Dependent Dysregulation in Nonalcoholic Fatty Liver Disease

Comprehensive understanding of the precise mode of action/adverse outcome pathway (MoA/AOP) of chemicals becomes a key step towards superseding the current repeated dose toxicity testing methodology with new generation predictive toxicology tools. The description and characterization of the toxicolo...

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Detalhes bibliográficos
Main Authors: Al Sharif, Merilin, Alov, Petko, Vitcheva, Vessela, Pajeva, Ilza, Tsakovska, Ivanka
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977565/
https://ncbi.nlm.nih.gov/pubmed/24772164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/432647
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