The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium

SIMPLE SUMMARY: The protease elastase found in neutrophil extracellular traps appears to be associated with equine endometrial fibrosis by its stimulatory effect on extracellular matrix (ECM) components, leading to an increase in collagen relative abundance. Metallopeptidases (MMP-2 and -9) are enzy...

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Detalhes bibliográficos
Publicado no:Animals (Basel)
Main Authors: Amaral, Ana, Fernandes, Carina, Rebordão, Maria Rosa, Szóstek-Mioduchowska, Anna, Lukasik, Karolina, Gawronska-Kozak, Barbara, Telo da Gama, Luís, Skarzynski, Dariusz J., Ferreira-Dias, Graça
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://ncbi.nlm.nih.gov/pubmed/32429399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10050863
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