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The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium

SIMPLE SUMMARY: The protease elastase found in neutrophil extracellular traps appears to be associated with equine endometrial fibrosis by its stimulatory effect on extracellular matrix (ECM) components, leading to an increase in collagen relative abundance. Metallopeptidases (MMP-2 and -9) are enzy...

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發表在:Animals (Basel)
Main Authors: Amaral, Ana, Fernandes, Carina, Rebordão, Maria Rosa, Szóstek-Mioduchowska, Anna, Lukasik, Karolina, Gawronska-Kozak, Barbara, Telo da Gama, Luís, Skarzynski, Dariusz J., Ferreira-Dias, Graça
格式: Artigo
語言:Inglês
出版: MDPI 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://ncbi.nlm.nih.gov/pubmed/32429399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10050863
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