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The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium

SIMPLE SUMMARY: The protease elastase found in neutrophil extracellular traps appears to be associated with equine endometrial fibrosis by its stimulatory effect on extracellular matrix (ECM) components, leading to an increase in collagen relative abundance. Metallopeptidases (MMP-2 and -9) are enzy...

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Bibliographische Detailangaben
Veröffentlicht in:Animals (Basel)
Hauptverfasser: Amaral, Ana, Fernandes, Carina, Rebordão, Maria Rosa, Szóstek-Mioduchowska, Anna, Lukasik, Karolina, Gawronska-Kozak, Barbara, Telo da Gama, Luís, Skarzynski, Dariusz J., Ferreira-Dias, Graça
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://ncbi.nlm.nih.gov/pubmed/32429399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10050863
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