The In Vitro Inhibitory Effect of Sivelestat on Elastase Induced Collagen and Metallopeptidase Expression in Equine Endometrium

SIMPLE SUMMARY: The protease elastase found in neutrophil extracellular traps appears to be associated with equine endometrial fibrosis by its stimulatory effect on extracellular matrix (ECM) components, leading to an increase in collagen relative abundance. Metallopeptidases (MMP-2 and -9) are enzy...

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Veröffentlicht in:Animals (Basel)
Hauptverfasser: Amaral, Ana, Fernandes, Carina, Rebordão, Maria Rosa, Szóstek-Mioduchowska, Anna, Lukasik, Karolina, Gawronska-Kozak, Barbara, Telo da Gama, Luís, Skarzynski, Dariusz J., Ferreira-Dias, Graça
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278485/
https://ncbi.nlm.nih.gov/pubmed/32429399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ani10050863
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