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Discovery of novel inhibitors of ribosome biogenesis by innovative high throughput screening strategies
Over the past two decades, ribosome biogenesis has emerged as an attractive target for cancer treatment. In this study, two high-throughput screens were used to identify ribosome biogenesis inhibitors. Our primary screen made use of the HaloTag selective labeling strategy to identify compounds that...
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| Publicado en: | Biochem J |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7278283/ https://ncbi.nlm.nih.gov/pubmed/31341008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20190207 |
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