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High-throughput Screening and Bayesian Machine Learning for Copper-dependent Inhibitors of Staphylococcus aureus

One potential source of new antibacterials is through probing existing chemical libraries for copper-dependent inhibitors (CDIs), i.e., molecules with antibiotic activity only in the presence of copper. Recently, our group demonstrated that previously unknown staphylococcal CDIs were frequently pres...

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Detalhes bibliográficos
Publicado no:Metallomics
Main Authors: Dalecki, Alex G., Zorn, Kimberley M., Clark, Alex M., Ekins, Sean, Narmore, Whitney T., Tower, Nichole, Rasmussen, Lynn, Bostwick, Robert, Kutsch, Olaf, Wolschendorf, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6467072/
https://ncbi.nlm.nih.gov/pubmed/30839007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8mt00342d
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