SN-38 Conjugated Gold Nanoparticles Activated by Ewing Sarcoma Specific mRNAs Exhibit In Vitro and In Vivo Efficacy

The limited delivery of chemotherapy agents to cancer cells and the nonspecific action of these agents are significant challenges in oncology. We have previously developed a customizable drug delivery and activation system in which a nucleic acid functionalized gold nanoparticle (Au-NP) delivers a d...

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Bibliografiska uppgifter
I publikationen:Bioconjug Chem
Huvudupphovsmän: Naumann, Jordan A., Widen, John C., Jonart, Leslie A., Ebadi, Maryam, Tang, Jian, Gordon, David J., Harki, Daniel A., Gordon, Peter M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7278042/
https://ncbi.nlm.nih.gov/pubmed/29412642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00774
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