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Epigenetic dysregulation of ACE2 and interferon-regulated genes might suggest increased COVID-19 susceptibility and severity in lupus patients

Infection caused by SARS-CoV-2 can result in severe respiratory complications and death. Patients with a compromised immune system are expected to be more susceptible to a severe disease course. In this report we suggest that patients with systemic lupus erythematous might be especially prone to sev...

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Vydáno v:medRxiv
Hlavní autoři: Sawalha, Amr H, Zhao, Ming, Coit, Patrick, Lu, Qianjin
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7277010/
https://ncbi.nlm.nih.gov/pubmed/32511654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.03.30.20047852
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