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Genome-wide Nucleotide-Resolution Mapping of DNA Replication Patterns, Single-Strand Breaks, and Lesions by GLOE-Seq

DNA single-strand breaks (SSBs) are among the most common lesions in the genome, arising spontaneously and as intermediates of many DNA transactions. Nevertheless, in contrast to double-strand breaks (DSBs), their distribution in the genome has hardly been addressed in a meaningful way. We now prese...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Sriramachandran, Annie M., Petrosino, Giuseppe, Méndez-Lago, María, Schäfer, Axel J., Batista-Nascimento, Liliana S., Zilio, Nicola, Ulrich, Helle D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7276987/
https://ncbi.nlm.nih.gov/pubmed/32320643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.03.027
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