Swapping of The N-Terminal Domain of Human Topoisomerase 1B with the Corresponding Plasmodium Falciparum Counterpart Strongly Impairs Enzyme Activity

BACKGROUND: DNA topoisomerases 1B are a class of ubiquitous enzyme that solves the topological problems associated with biological processes such as replication, transcription and recombination. Numerous sequence alignment of topoisomerase 1B from different species shows that the lengths of differen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Rep Biochem Mol Biol
Egile Nagusiak: Dasari, Jagadish Babu, Soren, Bini Chhetri, Ottaviani, Alessio, Tesauro, Cinzia, Marino, Simona, Messina, Beatrice, Fiorani, Paola
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Varastegan Institute for Medical Sciences 2020
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275839/
https://ncbi.nlm.nih.gov/pubmed/32582794
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