HSP90 overexpression potentiates the B-cell receptor and fibroblast growth factor receptor survival signals in chronic lymphocytic leukemia cells

Chronic lymphocytic leukemia (CLL) is still an incurable disease despite aggressive chemotherapies including the B-cell receptor (BCR) targeted-inhibitors. Therefore, we assessed the expression status of key signal mediators of the BCR pathway in CLL cells. Indeed, we detected aberrantly elevated le...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Mahmud, Hasan, Mendez, Mariana, Mukhopadhyay, Bedabrata, Holter-Chakrabarty, Jennifer, Ghosh, Asish K.
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2020
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7275782/
https://ncbi.nlm.nih.gov/pubmed/32547702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27409
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