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Liquid–liquid phase separation of type II diabetes-associated IAPP initiates hydrogelation and aggregation
Amyloidoses (misfolded polypeptide accumulation) are among the most debilitating diseases our aging societies face. Amyloidogenesis can be catalyzed by hydrophobic–hydrophilic interfaces (e.g., air–water interface in vitro [AWI]). We recently demonstrated hydrogelation of the amyloidogenic type II d...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275713/ https://ncbi.nlm.nih.gov/pubmed/32414928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1916716117 |
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