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Effects of hydroxyurea on CNV induction in the mouse germline
Copy number variants (CNVs) are important in genome variation and genetic disease, with new mutations arising frequently in the germline and somatic cells. Replication stress caused by aphidicolin and hydroxyurea (HU) is a potent inducer of de novo CNVs in cultured mammalian cells. HU is used extens...
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| Publicat a: | Environ Mol Mutagen |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275641/ https://ncbi.nlm.nih.gov/pubmed/30218578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22233 |
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