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The regulation and pharmacological modulation of immune complex induced type III IFN production by plasmacytoid dendritic cells
OBJECTIVE: Patients with systemic lupus erythematosus (SLE) have an ongoing interferon (IFN) production due to an activation of plasmacytoid dendritic cells (pDCs), which can be triggered to type I IFN synthesis by RNA containing immune complexes (RNA-IC). Considering emerging data suggesting a role...
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| Publicado no: | Arthritis Res Ther |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7275601/ https://ncbi.nlm.nih.gov/pubmed/32503683 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02186-z |
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