The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in T cells from patients with SLE

OBJECTIVES: Genetic variants in the transcription factor STAT4 are associated with increased susceptibility to systemic lupus erythematosus (SLE) and a more severe disease phenotype. This study aimed to clarify how the SLE-associated intronic STAT4 risk allele rs7574865[T] affects the function of im...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Ann Rheum Dis
Main Authors: Hagberg, Niklas, Joelsson, Martin, Leonard, Dag, Reid, Sarah, Eloranta, Maija-Leena, Mo, John, Nilsson, Magnus K, Syvänen, Ann-Christine, Bryceson, Yenan T, Rönnblom, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2018
Assuntos:
Basic and Translational Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6029643/
https://ncbi.nlm.nih.gov/pubmed/29475858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2017-212794
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados