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Relaxation of Extracellular Matrix Forces Directs Crypt Formation and Architecture in Intestinal Organoids
Intestinal organoid protocols rely on the use of extracellular scaffolds, typically Matrigel, and upon switching from growth to differentiation promoting media, a symmetry breaking event takes place. During this stage, the first bud like structures analogous to crypts protrude from the central body...
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| Veröffentlicht in: | Adv Healthc Mater |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274865/ https://ncbi.nlm.nih.gov/pubmed/31957249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201901214 |
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