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Relaxation of Extracellular Matrix Forces Directs Crypt Formation and Architecture in Intestinal Organoids

Intestinal organoid protocols rely on the use of extracellular scaffolds, typically Matrigel, and upon switching from growth to differentiation promoting media, a symmetry breaking event takes place. During this stage, the first bud like structures analogous to crypts protrude from the central body...

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Podrobná bibliografie
Vydáno v:Adv Healthc Mater
Hlavní autoři: Hushka, Ella A., Yavitt, F. Max, Brown, Tobin E., Dempsey, Peter J., Anseth, Kristi S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274865/
https://ncbi.nlm.nih.gov/pubmed/31957249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201901214
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