Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone

Hormone-dependent activation of enhancers includes histone hyperacetylation and mediator recruitment. Histone hyperacetylation is mostly explained by a bimodal switch model, where histone deacetylases (HDACs) disassociate from chromatin, and histone acetyl transferases (HATs) are recruited. This mod...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Præstholm, Stine M., Siersbæk, Majken S., Nielsen, Ronni, Zhu, Xuguang, Hollenberg, Anthony N., Cheng, Sheue-yann, Grøntved, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274477/
https://ncbi.nlm.nih.gov/pubmed/32453730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008770
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