Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone

Hormone-dependent activation of enhancers includes histone hyperacetylation and mediator recruitment. Histone hyperacetylation is mostly explained by a bimodal switch model, where histone deacetylases (HDACs) disassociate from chromatin, and histone acetyl transferases (HATs) are recruited. This mod...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Præstholm, Stine M., Siersbæk, Majken S., Nielsen, Ronni, Zhu, Xuguang, Hollenberg, Anthony N., Cheng, Sheue-yann, Grøntved, Lars
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274477/
https://ncbi.nlm.nih.gov/pubmed/32453730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008770
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