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Multiple mechanisms regulate H3 acetylation of enhancers in response to thyroid hormone
Hormone-dependent activation of enhancers includes histone hyperacetylation and mediator recruitment. Histone hyperacetylation is mostly explained by a bimodal switch model, where histone deacetylases (HDACs) disassociate from chromatin, and histone acetyl transferases (HATs) are recruited. This mod...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274477/ https://ncbi.nlm.nih.gov/pubmed/32453730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008770 |
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