Ultra-sensitive detection of Mycobacterium leprae: DNA extraction and PCR assays

Leprosy urgently needs a precise and early diagnostic tool. The sensitivity of the direct (bacilli staining, Mycobacterium leprae DNA) and indirect (antibody levels, T cell assays) diagnostics methods vary based on the clinical form. Recently, PCR-based M. leprae DNA detection has been shown to diff...

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Detalles Bibliográficos
Publicado en:PLoS Negl Trop Dis
Main Authors: Manta, Fernanda Saloum de Neves, Leal-Calvo, Thyago, Moreira, Suelen Justo M., Marques, Brunna L. C., Ribeiro-Alves, Marcelo, Rosa, Patrícia S., Nery, José Augusto C., Rampazzo, Rita de Cássia Pontello, Costa, Alexandre Dias Tavares, Krieger, Marco Aurelio, Moraes, Milton Ozório
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2020
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274454/
https://ncbi.nlm.nih.gov/pubmed/32453754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0008325
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