Emergence of Mycobacterium leprae Rifampin Resistance Evaluated by Whole-Genome Sequencing after 48 Years of Irregular Treatment

A case of Mycobacterium leprae rifampin resistance after irregular antileprosy treatments since 1971 is reported. Whole-genome sequencing from four longitudinal samples indicated relapse due to acquired rifampin resistance and not to reinfection with another strain. A putative compensatory mutation...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Avanzi, Charlotte, Maia, Raquel Cristina, Benjak, Andrej, Nery, José Augusto, Sales, Anna Maria, Miranda, Alice, Duppre, Nadia Cristina, Nogueira Brum Fontes, Amanda, Pereira da Silva, Tatiana, Olmo Pinheiro, Roberta, Neves-Manta, Fernanda, Moreira, Suelen Justo Maria, Busso, Philippe, Sarno, Euzenir Nunes, Suffys, Phillip Noel, Cole, Stewart Thomas, Moraes, Milton Ozório
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Epidemiology and Surveillance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7318023/
https://ncbi.nlm.nih.gov/pubmed/32340990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00330-20
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados