Large-Scale Gene Expression Signatures Reveal a Microbicidal Pattern of Activation in Mycobacterium leprae-Infected Monocyte-Derived Macrophages With Low Multiplicity of Infection

Leprosy is a disease with a clinical spectrum of presentations that is also manifested in diverse histological features. At one pole, lepromatous lesions (L-pole) have phagocytic foamy macrophages heavily parasitized with freely multiplying intracellular Mycobacterium leprae. At the other pole, the...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Leal-Calvo, Thyago, Martins, Bruna Leticia, Bertoluci, Daniele Ferreira, Rosa, Patricia Sammarco, de Camargo, Rodrigo Mendes, Germano, Giovanna Vale, Brito de Souza, Vania Nieto, Pereira Latini, Ana Carla, Moraes, Milton Ozório
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085500/
https://ncbi.nlm.nih.gov/pubmed/33936067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.647832
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