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Inhibition of CaMKII in Mitochondria Preserves Endothelial Barrier Function After Irradiation
Damage to the microvascular endothelium is an important part of normal tissue injury after radiation exposure and driven by the production of pro-oxidants. The Ca(2+)/calmodulin-dependent protein kinase II is present in the mitochondrial matrix (mitoCaMKII) where it regulates Ca(2+) uptake via the m...
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| 出版年: | Free Radic Biol Med |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7274136/ https://ncbi.nlm.nih.gov/pubmed/31711984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2019.11.012 |
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