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CaMKII (Ca(2+)/calmodulin-dependent kinase II) in mitochondria of smooth muscle cells controls mitochondrial mobility, migration and neointima formation
OBJECTIVE: To define the mechanisms by which mitochondria control VSMC migration and impact neointimal hyperplasia. APPROACH AND RESULTS: The multifunctional Ca(2+)/calmodulin-dependent kinase II (CaMKII) in the mitochondrial matrix of VSMC drove a feed-forward circuit with the mitochondrial Ca(2+)...
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| Publié dans: | Arterioscler Thromb Vasc Biol |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5970052/ https://ncbi.nlm.nih.gov/pubmed/29599132 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.118.310951 |
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